doi:10.1001/jama.2023.21835 Nicholls SJ, Ni W, Rhodes GM, et al
For women, significant hormone fluctuations during the years leading up to menopause ( perimenopause ) can cause disruptive symptoms like hot flashes, sleep problems, mood swings, weight changes, inflammation, and more
While preliminary evidence identifies ferroptosis as a key pathogenic factor in IgA nephropathylinked to GPX4 downregulation, Gd-IgA1-induced mesangial cell injury, and the PPARFABP1ACSL4 regulatory axisand validates ferroptosis inhibitors as potential therapeutics, several critical, insufficiently addressed research gaps persist
For others, it may be sleep quality, hormone balance, thyroid function, insulin resistance, inflammation, or overall metabolic health
Long-acting C-peptide and neuropathy in type 1 diabetes: a 12-month clinical trial